animalmodel相关论文
干眼症是临床常见的多因素眼表疾病，其发病机制复杂，其中免疫机制至关重要，但目前关于免疫炎症反应中发生的信号传导通路了解甚少，因此......
Alzheimer\'s disease (AD) is a neurodegenerative disorder. The pathology of AD is characterized by extracellular amylo......
The 2020 Nobel Prize in Chemistry recognized CRISPR-Cas9,a super-selective and precise gene editing tool.CRISPR-Cas9 has......
MicroRNA expression in animal models of amyotrophic lateral sclerosis and potential therapeutic appr
A review of recent animal models of amyotrophic lateral sclerosis showed a large number of miRNAs had altered levels of ......
This review addresses the accumulating evidence that live (not decellularized) allogeneic peripheral nerves are function......
Modeling subcortical ischemic white matter injury in rrodents: unmet need for a breakthrough in tran
Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraios......
MicroRNAs in laser-induced choroidal neovascularization in mice and rats: their expression and poten
Choroidal neovascularization characterizes wet age-related macular degeneration.Choroidal neovascularization formation i......
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Evaluation Study on Urine Metabolomics in Yinhuang(阴黄)Rat Model Induced by Triplet Factors of Rhubar
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Thinking Path and Method for Establishing the Disease/Chinese Medicine Syndrome Conjugated Pattern o
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Experimental animal models and inflammatory cellular changes in cerebral ischemic and hemorrhagic st
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The recent outbreak of coronavirus disease (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus ......
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Non-invasive determination of hepatic steatosis by acoustic structure quantification from ultrasound
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Induced pluripotent stem cells (iPS) represent an appealing cell source to develop disease-modeling assays, drug testing......
To provide experimental model for abdominal aortic aneurysm research and to optimize design of stent-graft,the authors e......
A Study To Determine The Temporal Relation Between The Development Of Osteoporosis And Osteonecrosis
Background:To develop rabbit models of glucocorticoid (GC)-induced femoral head osteonecrosis (ON) and osteoporosis (OP)......
Effects of Different Static Compression on the Intervertebral Disc:An in Vivo Bending Rat Tail Model
Purpose: To evaluate how different magnitude of compression induced degenerative changes using a bending rat tail model ......
PURPOSE: The study aims to develop a gradable and replicable animal model of human lumbar distraction SCI.METHODS: We bu......
Purpose: To explore influence of continuous illumination,luzindole and calmodulin antagonist,on success rate of making m......
Intrathecal decompression versus epidural decompression in the treatment of severe spinal cord injur
Objective: In the setting of severe spinal cord injury(SCI),there is no markedly efficacious clinical therapeutic regime......
Objective: To compare the difference of tumor growth between CTVT cell suspension group and tumor fragment group so as t......
The Experimental Study On The Effect Of Instrumentation Autoguided Growing Rod System On Growth Plat
[Objective] To evaluate effect of auto-guided growing rod system on spinal growth though animal experiment. [Methods] 6 ......
Mechanistic roles of osteopontin in the osteogenic stimulation in the Thoracic ligament flavum cells
Background:Ossification of the ligamentum flavum (OLF) and related osteogenic mechanisms have been studied for many year......
Background:To explore influence of continuous illumination,luzindole and calmodulin antagonist,on success rate of making......
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Background.It has been acknowledged that vertebral endplate fracture could promote the intervertebral disc degeneration(......
目的 Studies have demonstrated that Hedgehog signaling pathway is activated in human hepatocarcinoma,whether it is also ......
Comparison of subcutaneous vs intramuscular inoculation to establish a maxillofacial tumor model and
Purpose To compare subcutaneous vs intramuscular inoculation for establishing a maxillofacial VX2 tumor model and evalua......
Objective: To establish a rabbit model of MCs and analyze why the rabbit model is difficult to generate from the point o......
Intrathecal Decompression versus Epidural Decompression in the Treatment of Severe Spinal Cord Injur
Objective: In the setting of severe spinal cord injury (SCI), there is no markedly efficacious clinical therapeutic regi......
A comparison of surgical invasions for spinal nerve ligation with or without paraspinal muscle remov
Introduction:L5 spinal nerve ligation (SNL) in rats is one of the most popular models for studying neuropathic pain beca......
Geometric and Pathological Study of an Intracranial Dolichoectasia Model in Two Different Mouse Stra
Purpose To investigate the differential susceptibility to elastase-induced intracranial dolichoectasia (IADE) induction ......
Objective: To establish a simple,reliable,and stable animal model of complete spinal cord injury,and to evaluate its neu......
Dynamic contrast-enhanced MRI assesses renal function in rats at different phases of unilateral uret
Objective:To evaluate the temporal change of renal function prior and different time points after unilateral ureteral ob......
Objective To explore the feasibility and safety of establishing an animal training model for the reconstruction of diges......
Inhibition of TRPA1reduces airway inflammation and airway hyperresponsiveness in a murine model of a
目的 Transient receptor potential ankyrin 1(TRPA1)was involved in the pathogenesis of various respiratory diseases,such ......
Objective:Approximately 1％ of the worlds adult population is affected by joint pain and disability resulting from ankle o......
Expression of tissue factor and forkhead box transcription factor O-1 in a rat model for chronic thr
目的 Few reports have examined tissue factor (TF) and forkhead box transcription factor O-1 (FoxO1) expression in chroni......
A study to determine the temporal relation between the development of osteoporosis and osteonecrosis
Background:There are more patients treated with low dose of GCs under long-term conditions in clinical. Hence, it was di......
